Results 71 to 80 of about 687,122 (255)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Resource-efficient network attack detection using selective State Space Models

open access: yesНаучно-технический вестник информационных технологий, механики и оптики
The spread of vulnerable Internet of Things devices leads to an increase in the number of attacks on them, which requires the development of accurate and resource-efficient detection methods.
E. O. Zdornikov, I. Yu. Popov
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Strict System Equivalence of 2D Linear Discrete State Space Models

open access: yesJournal of Control Science and Engineering, 2012
The connection between the polynomial matrix descriptions (PMDs) of the well-known regular and singular 2D linear discrete state space models is considered.
Mohamed S. Boudellioua
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Standardised hearing loss risk profiles with state-space models

open access: yesMathematics in Medical and Life Sciences
Hearing loss is a growing public health concern, affecting millions and contributing to impaired communication, social isolation, and reduced quality of life.
M. Campi   +4 more
doaj   +1 more source

Forecasting Efficiency between State Space And ARIMA Models with Application [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2008
This research shows the forecasting using both of ARIMA and state space models. We firstly predict using ARIMA models, then we predict again after using ARIMA state space representation.
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Chemical language modeling with structured state space sequence models

open access: yesNature Communications
Generative deep learning is reshaping drug design. Chemical language models (CLMs) – which generate molecules in the form of molecular strings – bear particular promise for this endeavor.
Rıza Özçelik   +3 more
doaj   +1 more source

Bitemporal Remote Sensing Change Detection With State-Space Models

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Change detection in very-high-resolution remote sensing images has gained significant attention, particularly with the rise of deep learning techniques such as convolutional neural networks and Transformers.
Lukun Wang   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy