Results 201 to 210 of about 2,417,129 (288)

The effectiveness of Parenthood-Centred Psychotherapy on perinatal maternal depressive-anxiety symptoms and child development in a disadvantaged population. [PDF]

Front Psychol
Gomà M, Arias-Pujol E, Llairó A, Prims E, Ferrer J, Sastre L, Glover V, Nanzer N.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Unfolding newer innovations for tomorrow's emergencies and disasters 2024 (UNITED'24): international disaster medicine conference in Kerala, India. [PDF]

Front Public Health
Trulik KG, Joseph J, Mathew TA, Menon V, Alangaden KJ, Lambert SD, Jacob JC, Thrickoikal JJ, Rosenthal M, Burnham GM, Kumar VA.   +10 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Consistency-Driven Dual-Teacher Framework for Semi-Supervised Zooplankton Microscopic Image Segmentation. [PDF]

J Imaging
Li Z, Wang Y, Yuan D, Qi Y, Song X.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Association of motoric cognitive risk syndrome and incident mild cognitive impairment in community-dwelling older adults. [PDF]

Front Neurol
Zhang Y, Ma L, Ma Y, Chang J, Zhao Y, Gao X, Wu Y, Xing Y, Guo Y, Ma L, Wang Z, Tang Y.   +11 more
europepmc   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller, Lauren N. Coffey, Shelley R. H. Mockler, Katie M. Laubscher, Carrie M. Stephan, M. Bridget Zimmerman, Katherine D. Mathews   +6 more
wiley   +1 more source

Factors associated with major electrocardiographic abnormalities in chagas disease patients: SaMi-trop cohort. [PDF]

Int J Cardiol Heart Vasc
de Jesus Rodrigues MG, Sabino EC, Pinho Ribeiro AL, de Oliveira da Silva da Silva LC, Fernandes LF, Silveira Cardoso LD, Baldo MP, Pinto Filho MM, Ana Haikal DS, Cruz DS, Leite SF, Ferreira AM.   +11 more
europepmc   +1 more source