Results 111 to 120 of about 3,448,602 (316)

Development of the mountain areas: domestic and foreign context

open access: yesAgricultural and Resource Economics, 2016
It was specified that the current system of the development incitement of the mountainous and other problematic areas in Ukraine has a narrow set of promotion means.
Irina Kolodiychuk
doaj  

Providing Food Security for Kaliningrad Region

open access: yesВестник Российского экономического университета имени Г. В. Плеханова
The article analyzes organizational, economic and technical measures aimed at improving the quality of land in the Kaliningrad region as one of the strategically important direction of the region development.
K. N. Tseslik
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

STATE SUPPORT IN FISHERY

open access: yesCroatian Journal of Fisheries, 2004
By passing the law on state support in agriculture, fishery and forestry the former support system has been changed. Fishery support beneficiaries can use several kinds of support and help. Former financial stimulations for fishery regulated by law from 1995 to 1st January 2003 were settled by the production stimulation model.
Irena Jahutka   +2 more
openaire   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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