Results 151 to 160 of about 17,646,011 (251)

Phase I Randomized Study of SCAI-005 Ophthalmic Solution: Safety, Tolerability, and Pharmacokinetics in Healthy Korean Adults. [PDF]

Ophthalmol Sci
Kang J, Park K, Choi S, Han S, Hwang BE, Lee JH, Jang M, Chung EK, Cho H, Heo Y, Han S.   +10 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Organization of African Unity the ad hoc Commission on the Algeria-Morocco Border Dispute

, 1964
Ad hoc Commission on the Algeria-Morocco Border Dispute, Khartoum, 26 September 1964It is a draft recommendation of the ad hoc Commission on the Algeria-Morocco Border Dispute which was set up by the Council of the Organization of African Unity during ...
Organization of African Unity
core  

Aquahenosis: a non-pharmacological altered state of consciousness induced by floatation-REST in individuals with anxiety and depression. [PDF]

Neurosci Conscious
Tobel T, Cone A, Choquette E, Garland M, Johnson MA, Mink K, Lynch C, Frohlich J, Feinstein JS, Reggente N, Khalsa S.   +10 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Nipocalimab Phase 3 Dose Selection for Severe Hemolytic Disease of the Fetus and Newborn. [PDF]

J Clin Pharmacol
Zhou J, Xiong Y, Lam E, Ling LE, Saeed-Khawaja S, Komatsu Y, Vermeulen A, Samtani MN, Leu JH.   +8 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Unity

, 1956
Deutsche Unity-Gesellschaft für Praktisches Christentum, Unity-Europa, Gesellschaft für Dynamische Lebensgestaltung und Geistige Erneuerung   +1 more
core  

MR-Linac Successfully Guided the Treatment of a Free-Moving Mesenteric Mass. [PDF]

Precis Radiat Oncol
Wang X, Lim TY, Wang H, Dabaja BS, Yang J.   +4 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source