Results 61 to 70 of about 880,884 (291)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Prediction accuracy of discrete choice experiments in health-related research: a systematic review and meta-analysisResearch in context

EClinicalMedicine
Summary: Background: Discrete choice experiments (DCEs) are increasingly used to inform the design of health products and services. It is essential to understand the extent to which DCEs provide reliable predictions outside of experimental settings in ...
Ying Zhang, Thi Quynh Anh Ho, Fern Terris-Prestholt, Matthew Quaife, Esther de Bekker-Grob, Peter Vickerman, Jason J. Ong   +6 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Beef Producer Alliance Preferences for Vertical Coordination: A Bivariate Nested Panel Probit Approach

Journal of Agricultural and Resource Economics, 2019
Using a nested bivariate panel probit model, we quantify the perceived attribute values (PAV) that beef producers place on different information flows and alliance attributes.
Ibrahima Sall, Russell Tronstad, Satheesh Aradhyula   +2 more
doaj   +1 more source

Strategic response to a sequence of discrete choice questions [PDF]

According to neoclassical economic theory, the only stated preference elicitation format that can feasibly be employed in field studies to which truthful response can be the dominant strategy for all respondents is a single binary choice between the ...
Bennett, Jeffrey W., Hensher, David A., McNair, Ben J.   +2 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Options for possible changes to the blood donation service: health economics modelling

Health Services and Delivery Research, 2018
Background: Evidence is required on the cost-effectiveness of alternative changes to the blood collection service. Objectives: (1) To estimate the cost-effectiveness of alternative minimum interdonation intervals between whole-blood donations.
Richard Grieve, Sarah Willis, Kaat De Corte, M Zia Sadique, Neil Hawkins, Silvia Perra, Mark Pennington, Jenny Turner, Carmel Moore, Crispin Wickenden, Catharina Koppitz, Gavin Cho, David J Roberts, Gail Miflin, John A Cairns   +14 more
doaj   +1 more source

Railway and road discrete choice model for foreign trade freight between Antioquia and the Port of Cartagena

Ingeniería e Investigación, 2016
Most Colombian freight is transported on roads with barely acceptable conditions, and although there is a speculation about the need for a railway for freight transportation, there is not a study in Colombia showing the variables that influence the modal
J. D. Pineda-Jaramillo, I. Sarmiento, J. E. Córdoba   +2 more
doaj   +1 more source

When Are Preferences Consistent? The Effects of Task Familiarity and Contextual Cues on Revealed and Stated Preferences [PDF]

Traditionally, economists make a sharp distinction between stated and revealed preferences, viewing the latter as more fully meeting the assumptions of economic analysis.
Baruch Fischhoff, Felix Schlaepfer
core  

Stated and revealed heterogeneous risk preferences in educational choice [PDF]

, 2014
Stated survey measures of risk preferences are increasingly being used in the literature, and they have been compared to revealed risk aversion primarily by means of experiments such as lottery choice tasks.
Fossen, Frank M., Glocker, Daniela
core   +5 more sources