Results 81 to 90 of about 880,884 (291)

Awareness, interest, and preferences of primary care providers in using point-of-care cancer screening technology [PDF]

open access: yes, 2016
Well-developed point-of-care (POC) cancer screening tools have the potential to provide better cancer care to patients in both developed and developing countries.
Cho, Margaret   +5 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

The Comprehensiveness Dilemma of Cost-Benefit Analysis

open access: yesEuropean Journal of Transport and Infrastructure Research, 2013
Most project impacts on environment, climate, and health are not valued in markets or in choice situations similar to market transactions. Analysts have to go beyond revealed preferences to stated preference interviews and even to deliberative processes ...
Tore Sager
doaj   +1 more source

Environmental Policy when People's Preferences are Inconsistent, Non-Welfaristic, or simply Not Developed [PDF]

open access: yes
This paper discusses how a benevolent policy maker should act based on some, possibly non-welfaristic,ethical principle in cases where people's preferences are not perfectly informed,consistent and fully developed with regard to all goods, including all ...
Johansson-Stenman, Olof
core  

Preference uncertainty in stated preference studies: facts and artefacts

open access: yesApplied Economics, 2013
The ordinal scale and polychotomous choice methods are two widely used techniques for estimating preference uncertainty in stated preference studies. This article presents the results of two experiments that apply these estimation techniques. The first experiment was designed to compare and contrast the scores of the ordinal scale and polychotomous ...
Akter, Sonia, Bennett, Jeffrey
openaire   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A multicriteria analysis of stated preferences among freight transport alternatives [PDF]

open access: yes
Stated preferences data can be of different types: choice data, rankings or ratings. In all cases, these data can be used in different ways as inputs of econometric discrete choice models.
Christophe Bouffioux   +2 more
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Valuing the economic benefits of species recovery programmes

open access: yesPeople and Nature
Accounting for the values placed on nature by the public is key to successful policies in reversing ongoing biodiversity declines. However, biodiversity values are rarely included in policy decisions, resulting in poorer outcomes for people and nature ...
E. Browning   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy