The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Examination under anesthesia imaging changes surgeons' classification and treatment decisions of anterior posterior compression pelvic ring injuries. [PDF]
Therrien CC +13 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Toward an Affordable Density-Based Measure for the Quality of a Coupled Cluster Calculation. [PDF]
Jones GH, Weflen KE, Martin JML.
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Methodology for Static Pressure Measurement Under Confined Spatial Conditions in the Low-Pressure Range. [PDF]
Šabacká P +10 more
europepmc +1 more source
Single-Injection Liposomal Bupivacaine Adductor Canal Block for Pain Control and Recovery After Total Knee Arthroplasty: A Randomized Controlled Double‑Blinded Study. [PDF]
Wen J +8 more
europepmc +1 more source
Dynamic wrist imaging using four-dimensional CT: current concepts, clinical applications, and future perspectives. [PDF]
van der Heijden EPA +5 more
europepmc +1 more source

