Results 131 to 140 of about 26,063,160 (372)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Checking Contact Tracing App Implementations with Bespoke Static Analysis. [PDF]

open access: yesSN Comput Sci, 2022
Flood R, Chan SC, Chen W, Aspinall D.
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

STAТIC ANALYSIS OF CROSS STEEL TRUSSES WITH A RECTANGULAR GRID OF COLUMNS

open access: yesСовременная наука и инновации, 2022
The article presents a model for static analysis of cross structures on rectangular plans with different aspect ratios. The data are compared with the results of numerical and experimental research, including natural tests of experimental and industrial ...
Alexander S. Marutyan
doaj  

From Single-thread to Multithreaded: An Efficient Static Analysis Algorithm [PDF]

open access: yes, 2009
A great variety of static analyses that compute safety properties of single-thread programs have now been developed. This paper presents a systematic method to extend a class of such static analyses, so that they handle programs with multiple POSIX-style
Carre, Jean-Loup, Hymans, Charles
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Involuntary Transfer: A Vulnerability Pattern in Smart Contracts

open access: yesIEEE Access
Smart Contracts (SCs) communicate with each other using external calls. Their interactions can be malicious, resulting in the loss of Ether. One can blame the reentrancy attack for this exploitation.
Zulfiqar Ali Khan, Akbar Siami Namin
doaj   +1 more source

On the adequacy of static analysis warnings with respect to code smell prediction. [PDF]

open access: yesEmpir Softw Eng, 2022
Pecorelli F   +4 more
europepmc   +1 more source

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