Results 161 to 170 of about 26,063,160 (372)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Kinetic and Static Analysis of Poly-(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted 18F-Fluorthanatrace PET Images of Ovarian Cancer. [PDF]

open access: yesJ Nucl Med, 2022
Young AJ   +14 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Modelo para el análisis estático en grafos difusos basado en indicadores compuestos de centralidad

open access: yesRevista Cubana de Ciencias Informáticas, 2015
Fuzzy graphs have recently grown in popularity for decision support. Finding the most important node in the model has multiple applications. Static analysis in fuzzy graphs is mainly based in only one centrality measure, degree centrality.
Rafael Bello Lara   +3 more
doaj  

Static and dynamic stability analysis of the space shuttle vehicle-orbiter [PDF]

open access: yes
The longitudinal static and dynamic stability of a Space Shuttle Vehicle-Orbiter (SSV Orbiter) model is analyzed using the FLEXSTAB computer program. Nonlinear effects are accounted for by application of a correction technique in the FLEXSTAB system; the
Cavin, R. K.   +2 more
core   +1 more source

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