Results 81 to 90 of about 164,194 (353)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Effect of aquatic immersion on static balance
, 2014 The objective of this study was to quantitatively assess measures of static balance and limits of stability (LOS) in an aquatic environment compared with on land.
Andrew Miller +13 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The Comparison of Balance Ability between Judo Players and Non-athletes
, 2012 [[abstract]]This present study investigated the balance ability between elite judo players and nonathletes. The subjects consisted of two groups. The judo players group consisted of ten elite judo players with mean age 21.2 1.5 years and the second ...
Chiang, Ching-Cheng; Chiang, Jinn-Yen; Shiang, Tzyy-Yuang
core
Hubungan Single Leg Static Dengan Functional Balance Pada Remaja [PDF]
, 2016 Recently, in this era, adolescent tend to do less physical activity that will lead an effect on the sensory input coordination of visual, vestibular and somatosensory.
, Dwi Rosella Komala Sari, SSt.FT.,M.Fis +1 more
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Effect of Aquatic Immersion on Static Balance
, 2013 Objective To quantitatively assess measures of static balance and limits of stability (LOS) in an aquatic environment compared to on land. Methods Fifteen healthy, young adults (23 + or - 2 years) performed 90 s static balance trials on land and aquatic ...
Louder, Talin J.
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Method for static divergence analysis of sting-mounted wind tunnel models [PDF]
, 2005 Occurrence of static divergence will result in a catastrophic failure of wind tunnel models supported13; on sting or other types of support . The report presents an analysis method that can be used to design and/or13; verify the design of a model-balance-
Sundaramurthy, H
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