Results 121 to 130 of about 10,608,145 (391)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Influence of Circumferential Convergent Wedge Pocket on the Segmented Annular Seal’s Static and Dynamic Characteristics

Lubricants
Aiming at the problem of abnormal wear caused by the poor dynamic characteristics of aeroengine segmented annular seals, according to the hydrodynamic lubrication theory, based on the conventional structure featuring the Rayleigh step profile rectangular
Shuang Wang, Dan Sun, Zemin Yang, Wenfeng Xu, Huan Zhao   +4 more
doaj   +1 more source

Measurement and evaluation of static characteristics of rotary hydraulic motor

, 2014
The paper describes experimental equipment for measurement of static characteristics of rotary hydraulic motor. It is possible to measure flow, pressure, temperature, speed and torque by means of this equipment.
L. Hružík, M. Vašina, A. Bureček
semanticscholar   +1 more source

Research on fluidics, valves, and proportional amplifiers [PDF]

Research and development being conducted at the Systems and Controls Laboratory is reviewed. Static characteristics (supply, input, transfer, output, and noise characteristics) of laminar proportional amplifiers were investigated.

core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

STUDYING THE EFFECT OF AN ADDITIONAL ACTIVE RESISTANCE IN THE FIELD WINDING CIRCUIT ON STARTING CHARACTERISTICS OF SALIENT-POLE SYNCHRONOUS MOTORS

Electrical engineering & Electromechanics, 2018
On the basis of the developed method for calculating steady-state asynchronous operation modes of salient-pole synchronous motors, a procedure of mathematical modelling of the starting characteristics is proposed.
V. S. Malyar, A. V. Malyar
doaj   +1 more source

Dynamic and Static Characteristics of Rolling Rigid Bodies

Bulletin of JSME, 1986
Motion of a prismatic part, which rolls across a surface, is analyzed theoretically in consideration of stiffness and viscous damping about elastic deformation of the surface and edges of the part, and the motion is also investigated experimentally. The probability that the parts will come to rest in a particular natural resting aspect is derived in ...
Hiroshi Shimojima, Osamu Sato, Tsuyoshi Kaneko, Akihiko Saito   +3 more
openaire   +4 more sources

On some characteristics of the frequency equation of small vibrations of holonomic conservative systems with static couplings [PDF]

, 1956
Danilo Rašković
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Static and dynamic stability analysis of the space shuttle vehicle-orbiter [PDF]

The longitudinal static and dynamic stability of a Space Shuttle Vehicle-Orbiter (SSV Orbiter) model is analyzed using the FLEXSTAB computer program. Nonlinear effects are accounted for by application of a correction technique in the FLEXSTAB system; the
Cavin, R. K., Chyu, W. J., Erickson, L. L.   +2 more
core   +1 more source