Results 141 to 150 of about 10,938,300 (390)

Influence of Rib Cage on Static Characteristics of Scoliotic Spine. [PDF]

open access: yesAppl Bionics Biomech, 2020
Lin L   +6 more
europepmc   +1 more source

Static Characteristic Analysis of Multi-Layer Foil Thrust Bearing: Considering Parameter Effects

open access: yesLubricants
A modified static characteristic model for the multi-layer foil thrust bearing (MLFTB) is established. In this model, the finite difference method and the thick plate element are implemented, the compressible Reynolds equation is linearized by the Newton–
Yulong Jiang   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Static and dynamic characteristics of a piezoceramic strut [PDF]

open access: yes
The experimental study of a piezoceramic active truss is presented. This active strut is unique in that the piezoceramic configurations allow the stroke length of the strut not to be dependent on the piezoceramic material's expansion range but on the ...
Belvin, W. Keith   +2 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Free-flight wind-tunnel investigation of a four-engine sweptwing upper-surface blown transport configuration [PDF]

open access: yes
The dynamic stability and control characteristics of a four-engine turbofan transport model having an upper-surface blown jet flap were investigated by means of the free-flight technique in the Langley full-scale tunnel. The flight characteristics of the
Parlett, L. P.
core   +1 more source

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