Results 151 to 160 of about 10,505,009 (388)
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Static stability and control characteristics of two large-dihedral right triangular pyramid lifting reentry configurations at a Mach number of 3.05 [PDF]
Static stability and control characteristics of dihedral right triangular pyramid lifting reentry vehicle ...
Foss, W. E., Jr., Whitcomb, C. F.
core +1 more source
The Statical Characteristics of Pneumatic Micrometer (Part 6)
Tsuruo Tsukahara
openalex +2 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Research on fluidics, valves, and proportional amplifiers [PDF]
Research and development being conducted at the Systems and Controls Laboratory is reviewed. Static characteristics (supply, input, transfer, output, and noise characteristics) of laminar proportional amplifiers were investigated.
core +1 more source
Effect of Particle Characteristics on the Static Properties of Powder
Masafumi Arakawa+2 more
openalex +2 more sources
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Static stability characteristics of several raked-off circular and elliptical cones at mach 6.7 [PDF]
Static stability characteristics of circular and elliptical cones at hypersonic ...
Bernot, P. T.
core +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source