Results 31 to 40 of about 45,092 (259)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Static Shift Correction and Fractal Characteristic Analysis of Time-Frequency Electromagnetic Data
Fractal and FractionalThe static shift effect is a distortion in electromagnetic data that severely impacts exploration results. Traditional static effect correction methods are often ineffective, prone to overcorrection or undercorrection, and make it difficult to accurately
Yujian Hou +4 more
doaj +1 more source
Counting photons in static electric and magnetic fields [PDF]
The European Physical Journal C, 2013 We describe the electromagnetic field by the massless limit of a massive vector field in the presence of a Coulomb gauge fixing term. The gauge fixing term ensures that, in the massless limit, the longitudinal mode is removed from the spectrum and only the two transverse modes survive.
openaire +3 more sources
Energy transfer in a static electric field [PDF]
Journal of Luminescence, 1993 Abstract The issue of how the application of a static electric field can influence energy transfer between molecules is addressed. Several aspects are considered. First, in molecules of reasonably high symmetry where the donor decay or the acceptor excitation transition is electric dipole forbidden, the application of a static field can, by an ...
Andrews, David L., Bittner, Alexander M.
openaire +2 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Linear and nonlinear optical responses in Kitaev spin liquids
Physical Review Research, 2021 We theoretically study THz-light-driven high-harmonic generation (HHG) in the spin-liquid states of the Kitaev honeycomb model with a magnetostriction coupling between spin and electric polarization.
Minoru Kanega +2 more
doaj +1 more source
Fractal structure effect on electric field within thunderclouds
Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2021 The paper considers the degree of fractal structure impact on the electric field intensity inside thunderstorm clouds using the apparatus of fractional integrodifferentiation.
Kumykov, T.S.
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
EnergiesThe insulation performance of vacuum arc interrupters greatly affects the reliability of vacuum circuit breakers. Optimizing the electric field distribution of a vacuum arc interrupter can improve its insulation performance.
Naming Zhang +5 more
doaj +1 more source