Results 191 to 200 of about 1,066,098 (345)

Metamorphic Flexure Bearings for Extended Range of Motion. [PDF]

J Mech Des N Y
Taylor CR, Flanagan W, Jones TH, Lim HK, Hopkins JB, Clites TR.   +5 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Onboard visual micro-servoing on robotic surgery tools. [PDF]

Microsyst Nanoeng
Chen X, Kiziroglou ME, Yeatman EM.
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Physics-Informed Neural Networks for Depth-Dependent Constitutive Relationships of Gradient Nanostructured 316L Stainless Steel. [PDF]

Materials (Basel)
Li H, Cheng Y, Wang Z, Wang X.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Optimal Design for a Novel Compliant XY Platform Integrated with a Hybrid Double Symmetric Amplifier Comprising One-Lever and Scott-Russell Mechanisms Arranged in a Perpendicular Series Layout for Vibration-Assisted CNC Milling. [PDF]

Micromachines (Basel)
Dang MP, Luong AK, Le HG, Tran CT.
europepmc   +1 more source

Static mechanical properties of hybrid RTM-made composite I- and Π-beams under three-point flexure

, 2015
Fu Yu, J. Xiong, Chuyang Luo, Yu Xinyao
semanticscholar   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Optimized Design of a Sub-Arc-Second Micro-Drive Rotary Mechanism Based on the Swarm Optimization Algorithm. [PDF]

Micromachines (Basel)
Zhang N, Wang D, Li K, Lv Z, Gui H, Yang Y, Yang M.   +6 more
europepmc   +1 more source