Results 101 to 110 of about 584,893 (305)

Damage and failure mechanism of pre-static loaded rock under cyclic impact

Meitan xuebao
To study the damage and failure mechanism of rocks under the coupling effect of high ground stress static load and cyclic impact disturbance generated by mining and excavation, the multi-strain rate dynamic static superposition rock mechanics test system
Hanpeng WANG, Wei WANG, Bing ZHANG, Tinglin QIU, Fubin HOU   +4 more
doaj   +1 more source

Failure mechanics in low-velocity impacts on thin composite plates [PDF]

Eight-ply quasi-isotropic composite plates of Thornel 300 graphite in Narmco 5208 epoxy resin (T300/5208) were tested to establish the degree of equivalence between low-velocity impact and static testing.
Elber, W.
core   +1 more source

An overview and comparative analysis of Recurrent Neural Networks for Short Term Load Forecasting

, 2017
The key component in forecasting demand and consumption of resources in a supply network is an accurate prediction of real-valued time series. Indeed, both service interruptions and resource waste can be reduced with the implementation of an effective ...
Bianchi, Filippo Maria, Jenssen, Robert, Kampffmeyer, Michael C., Maiorino, Enrico, Rizzi, Antonello   +4 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Determination of load sequence effects on the degradation and failure of composite materials [PDF]

A theoretical model was established to predict the fatigue behavior of composite materials, with emphasis placed on predictions of the degradation of residual strength and residual stiffness during fatigue cycling.
Jones, D. L., Yang, J. N.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Data-driven approach to enhance deep foundation safety: reliable methods for predicting bored pile capacity

International Journal of Geo-Engineering
The interpretation methods used to predict ultimate pile capacity from load-settlement curves yield varied results due to their unique assumptions and limitations.
Usman Hasan Jalali, Badee Alshameri, Muhammad Hamza Khalid, Waqas Hassan, Lokmane Abdeldjouad, S. Muhammad Jamil, Hassan Farooq, Zain Maqsood   +7 more
doaj   +1 more source

A study of environmental characterization of conventional and advanced aluminum alloys for selection and design. Phase 2: The breaking load test method [PDF]

A technique is demonstrated for accelerated stress corrosion testing of high strength aluminum alloys. The method offers better precision and shorter exposure times than traditional pass fail procedures.
Brazill, R. L., Bretz, P. E., Bucci, R. J., Ponchel, B. M., Sprowls, D. O.   +4 more
core   +1 more source

Experimetal measurement of soil-prestressed foundation interaction [PDF]

, 2016
Several experimental measurements of reinforced concrete slab – subsoil interaction are compared with numerical analysis of shallow foundation by means of FEM.
Labudková, Jana, Mynarčík, Petr, Čajka, Radim   +2 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source