Results 51 to 60 of about 270,891 (266)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Analysis of Thermo-Hydrodynamic Lubrication of Three-Lobe Semi-Floating Ring Bearing Considering Temperature–Viscosity Effect and Static Pressure Flow

Lubricants
High-power diesel engine turbochargers predominantly utilize floating ring bearings as their primary supporting components. To further enhance their load capacity, multi-lobe noncircular bearings have been progressively employed.
Jiwei Dong, Huabing Wen, Junchao Zhu, Junhua Guo, Chen Zong   +4 more
doaj   +1 more source

On the performance of turbo codes in quasi-static fading channels [PDF]

Proceedings. International Symposium on Information Theory, 2005. ISIT 2005., 2005
To appear in the Proceedings of the 2005 IEEE International Symposium on Information Theory, Adelaide, Australia, September 4-9 ...
Miguel R. D. Rodrigues, Ioannis Chatzigeorgiou, Ian J. Wassell, Rolando A. Carrasco   +3 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Effects of Structure Parameters on Static Performance of Gas Foil Bearings Based on a New Fully Coupled Elastic–Aerodynamic Model

Lubricants
Accurately predicting the performance of gas foil bearings (GFBs) is important. This paper presents a new fully coupled elastic–aerodynamic model for analyzing the static performance of gas foil journal bearings (GFJBs).
Pengjing Ding, Yang Hu, Xiaojing Wang, Yonggang Meng   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Experimental study on the effect of the riveting process on the bending resistance of beams composed of galvanized Q235 steel

High Temperature Materials and Processes
In this article, a hollow flange beam (ARHFB) composed of self-piercing rivet (SPR) and galvanized steel sheet was proposed, and the process parameters and mechanical properties of SPR connection technology for Q235 galvanized steel sheet were studied ...
Xue Jingya, Wu Qing, Chen Xiaomiao, Ma Shiliang, Wang Yunqing, Mo Jianbing, Yang Jianming   +6 more
doaj   +1 more source