Results 121 to 130 of about 234,924 (310)

INTERNAL PRESSURE MANAGEMENT SYSTEM

, 2015
A device including an implantable sensor having a membrane displaceable in response to physical phenomena outside the sensor, wherein the device is configured to equalize a static pressure difference between an ambient environment and a back volume of ...
Paris, Francesca, Huber, Alexander, Wiskerke, Pieter, Obrist, Dominik, Landolt, Andrin, Walraevens, Joris, Prochazka, Lukas   +6 more
core  

Detection of impaired cerebral autoregulation improves by increasing arterial blood pressure variability

, 2013
Although the assessment of dynamic cerebral autoregulation (CA) based on measurements of spontaneous fluctuations in arterial blood pressure (ABP) and cerebral blood flow (CBF) is a convenient and much used method, there remains uncertainty about its ...
Simpson, David M., Bush, Glen, Allen, Robert, Birch, Anthony A., Potter, John F., Panerai, Ronney B., Fan, Lingke, Katsogridakis, Emmanuel   +7 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

UNCERTAINTY IN STATIC PRESSURE CORRECTION IN A SUBSONIC WIND TUNNEL

, 2004
The static pressure p on the subsonic Wind Tunnel of the Aerodynamic Testing Laboratory of the Institute of Aeronautics and Space IAE, Aerospace Technical Center CTA, is measured using an absolute pressure sensor, located on the upper test section wall.
Reis, M. L. C. C., Mello, O. A. F., Chisaki, M.   +2 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Reference Static Pressure Effect on Fluctuating Wind Pressure on Roofs of Low-Rise Buildings in Open-Circuit Wind Tunnels

Buildings
The structural characteristics of open-circuit wind tunnels result in internal static pressure instability, which can affect the accuracy of wind pressure coefficient measurements on rigid models of low-rise buildings. To address this issue, a Pitot tube
Mengchang Yang, Enguang Wang, Il-Seung Yang   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Simulation of Obstruction in Static Pressure Inlet [PDF]

, 2016
Simulacija prikaza začepljenja otvora statičkog tlaka zrakoplova izrađena je u programskom okruženju Matlab Simulink. Pomoću blokova i dijagrama toka ostvaren je algoritam te su rezultati korišteni za simulaciju. Objašnjeni su odnosi među tlakovima zraka,
Pejković, Marko
core  

Aging effect of osteoprotegerin and receptor activator of nuclear factor-κB ligand expression in human periodontal ligament cells under continuous static pressure. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi, 2022
Wu J, Cui Z, Han Y, Li W.
europepmc   +1 more source