Results 171 to 180 of about 234,924 (310)

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Leakage analysis of gasketed flange joints under combined internap pressure and thermal loading

, 2011
Leakage in Gasketed Flanged Joints (GFJs) have always been a great problem for the process industry. The sealing performance of a GFJ depends on its installation and applied loading conditions.
Khan, Kamran Ahmed, Abid, Muhammad, Nash, David, Chatta, Javed Ahmad   +3 more
core  

Mechanical characteristics and calculation method of static pressure pile installation for PHC pipe piles in sandy soil foundation with pebble interlayer. [PDF]

Sci Rep
Zhou X, Yang C, Ming X, Dai M, Lu W, Zhang F.   +5 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Impact of ultrasonic probe type, frequency, and static pressure on large-scale graphene exfoliation. [PDF]

Ultrason Sonochem
Gao M, Zong H, Yu L, Yao J, Zhao S, Zhou Y, Li Y, Zhou Y, Zhang J, Li R.   +9 more
europepmc   +1 more source

Synchrotron-based visualization and segmentation of elastic lamellae in the mouse carotid artery during quasi-static pressure inflation. [PDF]

J R Soc Interface, 2019
Trachet B, Ferraro M, Lovric G, Aslanidou L, Logghe G, Segers P, Stergiopulos N.   +6 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Effect of static pressure on ultrasonic liquid phase exfoliation of few-layer graphene. [PDF]

Ultrason Sonochem
Zong H, Gao M, Ul Hassan Mohsan A, Lin Y, Zhou Y, Yu L, Zhao S, Li Y, Zhang J.   +8 more
europepmc   +1 more source