Results 31 to 40 of about 16,957 (295)

Alleviating Aspirin-Induced Gastric Injury by Binding Aspirin to β-Lactoglobulin

Drug Design, Development and Therapy, 2022
Jin Chen,1,* Min Gong,1,* Zhuo Huang,1 Fang Wang,2 Yajing Wang,3 Zuquan Hu,1 Zhu Zeng,1 Yun Wang2 1Key Laboratory of Biology and Medical Engineering/Immune Cells and Antibody Engineering Research Center of Guizhou Province, School of Biology and ...
Chen J, Gong M, Huang Z, Wang F, Wang Y, Hu Z, Zeng Z, Wang Y   +7 more
doaj  

Tyrosine-Mediated Static and Dynamic Quenching of a Receptor Tyrosine Kinase Biosensor Reveals Inhibitor Binding Modes and Kinase Conformations. [PDF]

ACS Chem Biol
Baker ZD, Thompson AR, Thomas DD, Levinson NM.   +3 more
europepmc   +2 more sources

Fluorescence Quenching of Aromatic Amino Acids by Rhodium Nanoparticles

Substantia
In this paper, the fluorescence quenching of the aromatic amino acids tyrosine and tryptophan by rhodium nanoparticles has been investigated.The choice of rhodium nanoparticles was determined by the fact that the plasmonic maximum of the nanoparticles ...
Elizaveta Demishkevich, Alexander Zozulya, Andrey Zyubin, Ivan Lyatun, Ilia Samusev   +4 more
doaj   +1 more source

Simulação Monte Carlo de mecanismo de transferência de energia de excitação eletrônica: modelo de Perrin para a supressão estática da luminescência

Química Nova, 2011
A software based in the Monte Carlo method has been developed aiming the teaching of the Perrin´s model for static luminescence quenching. This software allows the student to easily simulate the luminescence decays of emissive molecules in the presence ...
João Batista Marques Novo, Lauro Camargo Dias Júnior   +1 more
doaj   +1 more source

Mechanistic interaction study of 5,6-Dichloro-2-[2-(pyridin-2-yl)ethyl]isoindoline-1,3-dione with bovine serum albumin by spectroscopic and molecular docking approaches

Saudi Pharmaceutical Journal, 2019
A synthesized and promising biologically hypoglycemic compound 5,6-Dichloro-2-[2-(pyridin-2-yl)ethyl]isoindoline-1,3-dione (5e) was studied for its binding to a model protein (bovine serum albumin; BSA) by spectroscopic and molecular simulation ...
Mohammed M. Alanazi, Abdulrahman A. Almehizia, Ahmed H. Bakheit, Nawaf A. Alsaif, Hamad M. Alkahtani, Tanveer A. Wani   +5 more
doaj   +1 more source

Effect of ultrasonic rolling on the surface integrity and corrosion properties of GCr15 steel before and after quenching

Materials Research Express, 2022
Two new surface strengthening processes,Ultrasonic rolling treatment before and after quenching were investigated on GCr15 steel. The surface integrity and corrosion were tested and ABAQUS simulation was conducted for the two processes.
Yongchen Wang, Jianghai Lin, Yanshuang Wang, Xiuli Fu   +3 more
doaj   +1 more source

Interactions of Amino Group Functionalized Tetraphenylvinyl and DNA: A Label-Free “On-Off-On” Fluorescent Aptamer Sensor toward Ampicillin

Biosensors, 2023
As a type of aggregation-induced emission (AIE) fluorescent probe, tetraphenylvinyl (TPE) or its derivatives are widely used in chemical imaging, biosensing and medical diagnosis.
Weifu Geng, Yan Feng, Yu Chen, Xin Zhang, Haoyi Zhang, Fanfan Yang, Xiuzhong Wang   +6 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Ultrafast fluorescence dynamics of NADH in aprotic solvents: Quasi-static self-quenching unmasked

Journal of Photochemistry and Photobiology A: Chemistry, 2022
We have recently provided some experimental evidence that there are ultrafast quenched conformation(s) ("dark states") of NADH. In this paper, the ultrafast fluorescence dynamics of NADH free in aprotic solvents (DMSO/DMF) has been investigated, using both a femtosecond up-conversion spectrophotofluorometer and a picosecond time-correlated single ...
Haoyang Li, Simin Cao, Jinquan Chen, Sanjun Zhang, Jianhua Xu, Jay R. Knutson   +5 more
openalex   +4 more sources