Results 41 to 50 of about 194,174 (265)
The inverted V-tail is equipped in a twin-boom UAV,whose intersection angle can influence the aerodynamic characteristics and static stability. A twin-boom UAV with inverted V-tail is proposed,and compared with the U-tail configuration by numerical ...
WANG Xiaolu +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Assessment of Propulsion Patterns for Hybrid Wing Configuration Aircraft with Embedded Propellers
This study employs computational fluid dynamics (CFD) to investigate the aerodynamic performance and static stability of hybrid wing aircraft, considering the interference of counter-rotating embedded propellers. Extensive numerical verification has been
Xiaolu Wang +4 more
doaj +1 more source
This study examines how the congestus mode of tropical convection is expressed in numerical simulations of radiative‐convective equilibrium (RCE). We draw insights from the ensemble of cloud‐resolving models participating in the RCE Model Intercomparison
Adam B. Sokol, Dennis L. Hartmann
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
75-mm Wingspan Fixed-Wing Nano Air Vehicle With a Novel Aircraft Configuration
The development of a fixed-wing nano air vehicle that fits inside a cube of 75 mm is described in this paper. A novel aircraft configuration that satisfies the static and dynamic stability and the mission performance requirements is developed.
Jinraj V. Pushpangathan +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

