Results 81 to 90 of about 183,815 (267)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A Practical Method for Investigation of Aerodynamic and Longitudinal Static Stability of Wing-in-Ground Effect

International Journal of Maritime Technology, 2015
The purpose of this paper is to present a fast, economical and practical method for mathematical modeling of aerodynamic characteristics of rectangular wing-in-ground effect (WIG).
Mohammad Saeed Seif, Mohammad Tavakoli
doaj  

Does kinesiotaping can improve static stability of the knee after anterior cruciate ligament rupture? A randomized single-blind, placebo-controlled trial. [PDF]

BMC Sports Sci Med Rehabil, 2021
Ogrodzka-Ciechanowicz K, Głąb G, Ślusarski J, Gądek A, Nawara J.   +4 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Descriptive Study of the Influence of Foot Type on Physical Characteristics, Laxity, Strength and Baropodometry in Children Aged 5 to 10 Years

Applied Sciences
Background: Foot morphology in children is a crucial factor influencing multiple aspects of their physical development. Between the ages of 5 and 10 years, the critical period of child development is when the movement and stability patterns are ...
Cristina Molina-García, Francisco Álvarez-Salvago, Clara Pujol-Fuentes, Andrés López-del-Amo-Lorente, Laura Ramos-Petersen, Carlos Martínez-Sebastián, Antonio Martínez-Amat, José Daniel Jiménez-García, Manuel De Diego-Moreno   +8 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Combined Aerobic and Strength Training Improves Dynamic Stability and can Prevent against Static Stability Decline in Postmenopausal Women: A Randomized Clinical Trial. [PDF]

Rev Bras Ginecol Obstet, 2023
Marques ACF, Rossi FE, Neves LM, Diniz TA, Messias IA, Barela JA, Horak FB, Júnior IFF.   +7 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A comparative study of the effect of soft and hard cervical collars on static postural

Ṭibb-i Tavānbakhshī, 2013
Background and Aim: Using cervical collars is one of the treatment methods for releaving cervical pain. The effect of limb orthotics on proprioception and postural stability has been suggested.
Minoo Khalkhali Zavieh, MirHamed Edalat-Haghi, Khosro Khademi-Kalantari, Abbas Rahimi, Mehdi Rezaee, Seyyed Mehdi Tabatabaee   +5 more
doaj  

METHOD OF ASSESSING THE LATERAL STABILITY WHILE ENCOUNTERING AN OBSTACLE UNDER THE TERMS OF WHEELS COUPLING [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2017
The movement of vehicles over a rough terrain is connected whith the risk of tipping. It has been established that the most dangerous moment is the transition from the horizontal plane of movement to an inclined one, which results in excitations of ...
A. Bashynskyi
doaj