Results 121 to 130 of about 1,758,742 (306)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Test method for static parameter of unipolar ADC
Dianzi Jishu YingyongThe static parameters of analog to digital converter (ADC) include differential nonlinearity (DNL) and integral nonlinearity (INL). The main method to measure static parameters is the code density histogram method.The traditional code density histogram ...
Zhu Qing, Wei Kai, Tao Qingping
doaj +1 more source
Summary of static load test of the Mod-0 blade [PDF]
A static load test was performed on the spare Mod-0 wind turbine blade to define load transfer at the root end of the blade, and to validate stress analysis of this particular type of blade construction (frame and stringer). Analysis of the load transfer
Miller, D. R.
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Pile–Soil Interaction during Static Load Test
Studia Geotechnica et MechanicaThis study highlights the possibility of determining the shear stress distribution along the skin of a pile, which represents skin resistance. Geotechnical engineering is plagued by the challenge of designing appropriate piles as a sufficient foundation ...
Siemaszko Paweł
doaj +1 more source
A unique facility for V/STOL aircraft hover testing [PDF]
The Langley Impact Dynamics Research Facility (IDRF) was modified to obtain static force and moment data and to allow assessment of aircraft handling qualities during dynamic tethered hover flight. Test probe procedures were also established. Static lift
Culpepper, R. G. +3 more
core +1 more source
NASTRAN applications to aircraft propulsion systems [PDF]
, 1975 The use of NASTRAN in propulsion system structural integration analysis is described. Computer support programs for modeling, substructuring, and plotting analysis results are discussed.
Beste, D. L., White, J. L.
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
STATIC VS DYNAMIC SECURITY TESTING
, 2023 This slide deck covers the differences between static (SAST) and dynamic (DAST) application security testing. It provides relevant information for those aiming to enhance their cybersecurity defenses while simultaneously demonstrating the importance of application security testing (AST).
openaire +1 more source