Results 51 to 60 of about 402,416 (268)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Study on Anti-collapse Performance of Double Web Angles Connection Under Different Span Ratios

open access: yes工程科学与技术, 2017
:According to alternative load path method,three double-span assemblies with double web angles connection based on different span ratios (1.0:0.6,1.0:1.0,1.0:1.4) of steel frame were chosen as the research objects.The failure mode,mechanical behavior,the
钟炜辉, 孟宝, 郝际平
doaj  

Experimental and Analytical Investigation of Transverse Bending Resistance in Steel Threaded Joints

open access: yesApplied Sciences
Rod ends are critical structural components primarily designed to sustain axial loads in mechanical and aeronautical assemblies. However, operational conditions may involve transverse loading, which induces significant bending stresses concentrated in ...
Maurizio Arena   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Embedded Software Static Test Technology

open access: yes机车电传动, 2017
Embedded software quality greatly influences on the reliability of embedded system, and the defects will cause serious consequences. To reduce development cost and shorten development cycle of embedded software, earlier static test in soft coding stage ...
YANG Ying   +4 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Effect of Sample Dimensions on Static Bending Test

open access: yesFloresta e Ambiente, 2020
This study aimed to evaluate the static bending strength (fM) and modulus of elasticity (MOE) to static bending values of Eucalyptus grandis samples produced in different dimensions.
Luciano Junqueira Costa   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Report on the Differential Testing of Static Analyzers

open access: yesActa Cybernetica, 2020
Program faults, best known as bugs, are practically unavoidable in today's ever growing software systems. One increasingly popular way of eliminating them, besides tests, dynamic analysis, and fuzzing, is using static analysis based bug-finding tools.
Gábor Horváth 0005   +2 more
openaire   +3 more sources

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