Results 71 to 80 of about 1,115,389 (312)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Estimation of the compaction characteristics of soils using the static compaction method
Bulletin of the Mineral Research and Exploration, 2020 Ground improvement using mechanical stabilization is commonly applied by performing the standard Proctor compaction test, which requires a significant quantity of soil, usually obtained from open pits.
Kamil Kayabalı +5 more
doaj +1 more source
Dynamic Specification Tests for Static Factor Models [PDF]
We derive computationally simple score tests of serial correlation in the levels and squares of common and idiosyncratic factors in static factor models.
Enrique Sentana, Gabriele Fiorentini
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Static load tests on piles in moraine soil layer
Yantu gongcheng xuebaoAiming at the thick moraine soil layer at Luding Dadu River Bridge on Ya'an-Kangding expressway, the static load tests on 7 model piles are carried out in the field surface and experimental adit, the horizontal force-displacement relations are analyzed ...
GUO Xifeng 1, 2 , ZENG Yong 1, CHENG Qiang 3, XIN Xingfu 4
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Extended flight evaluation of a near-term pitch active control system [PDF]
Fuel savings can be achieved by moving the center of gravity of an aircraft aft which reduces the static stability margin and consequently the trim drag. However, flying qualities of an aircraft with relaxed static stability can be significantly degraded.
Chong, Michael G. +2 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Wind-tunnel free-flight investigation of a model of a forward-swept-wing fighter configuration [PDF]
A wind-tunnel free-flight investigation was conducted to study the dynamic stability characteristics of a model of a forward-swept-wing fighter-airplane configuration at high angles of attack.
Grafton, S. B. +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source