Results 111 to 120 of about 129,031 (251)

Electronic Patient File‐Embedded Model‐Informed Precision Dosing Compared with Physician Dosing of Tacrolimus in Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers, Pieter Annaert, Borefore Jallah, Maarten Naesens, Maxine Teuns, Annouschka Laenen, Ruben Faelens   +6 more
wiley   +1 more source

PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature

Clinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou, Estella S. Poloni, José A.G. Agúndez, Raquel L.F. Teixeira, Erin C. Boone, Adalberto Rezende Santos, Michelle Whirl‐Carrillo, Katrin Sangkuhl, Teri E. Klein, Mariam R. Habil, Giannoulis Fakis, Rodney F. Minchin, David W. Hein, Sotiria Boukouvala, Andrea Gaedigk   +14 more
wiley   +1 more source

Ten quick tips for developing a reproducible Shiny application. [PDF]

PLoS Comput Biol
Brun J, Janée G, Curty RG.
europepmc   +1 more source

Challenges and Enablers in Embedding SDGs Within Sustainability Reports

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study explores how Sustainable Development Goals (SDGs) are integrated into sustainability reporting (SR), emphasizing the role of reporting in advancing transparency and sustainable development. Using a systematic literature review of 139 academic articles, the research identifies four thematic clusters: Communication, Determinant ...
Francesco Pacchera, Mariagrazia Provenzano, Cecilia Silvestri, Fabrizio Rossi, Alessandro Ruggieri   +4 more
wiley   +1 more source

Enhancing digital health literacy in adolescents: evaluation of a co-designed educational app. [PDF]

BMC Public Health
Hawkins A, Taba M, Caldwell PHY, Kang M, Skinner SR, McCaffery K, Scott KM.   +6 more
europepmc   +1 more source

Understanding Consumer Behaviour and the Circular Economy Transition in Sustainable Fashion: A Systematic Literature Review

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The fashion industry plays a key role towards global sustainability goals, yet remains among the most sustainability‐impacting sectors. Since 2020, several disruptions—including the Covid‐19 pandemic, geopolitical instability, and ambitious sustainability policies—have dramatically reshaped how consumers interact with fashion. In response, the
Chiara Marinelli
wiley   +1 more source

VueGen: automating the generation of scientific reports. [PDF]

Bioinform Adv
Ayala-Ruano S, Webel H, Santos A.
europepmc   +1 more source

English across the four nations: A ‘home international’ comparison of secondary English curricula in the UK

The Curriculum Journal, EarlyView.
Abstract Every child across the UK is expected to study English until the age of 16. The subject is understood to be a core and foundational element of pupils' curriculum entitlement across their school lives, and success in English is a key determinant for influencing individuals' future trajectories, and for impacting wider economic and social ...
Rebecca Morris, Wendy Ramku
wiley   +1 more source

Utilization of Eye-Tracking Metrics to Evaluate User Experiences-Technology Description and Preliminary Study. [PDF]

Sensors (Basel)
Falkowska J, Sobecki J, Falkowski M.
europepmc   +1 more source

Local realities, global discourses and decolonising the curriculum in a post‐92 UK context: Academic voices on enacting decolonial curriculum change

The Curriculum Journal, EarlyView.
Abstract This study explored how lecturers in a post‐92 UK university conceptualise and enact decolonial curriculum principles within their teaching and programme design. Drawing on semi‐structured interviews with academic staff across multiple disciplines, the research adopts a qualitative, phenomenologically informed approach to examine the interplay
Reece Sohdi
wiley   +1 more source