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Tubing modifications for countercurrent chromatography (CCC): Stationary phase retention and separation efficiency

Analytica Chimica Acta, 2015
Countercurrent chromatography (CCC) is a separation technique in which two immiscible liquid phases are used for the preparative purification of synthetic and natural products. In CCC the number of repetitive mixing and de-mixing processes, the retention of the stationary phase and the mass transfer between the liquid phases are significant parameters ...
Michael, Englert, Walter, Vetter
openaire   +3 more sources

Retention and selectivity of stationary phases for hydrophilic interaction chromatography

Journal of Chromatography A, 2011
More and more polar stationary phases have become available for the separation of small polar compounds in the past decade as hydrophilic interaction chromatography (HILIC) continues to find applications in new fields (e.g., metabolomics and proteomics). Bare silica phases remain popular, especially in the bio-analytical area.
Yong, Guo, Sheetal, Gaiki
openaire   +4 more sources

Retention mechanisms in reversed-phase liquid chromatography. Stationary-phase bonding density and partitioning

Analytical Chemistry, 1989
The partitioning model of retention for reversed-phase liquid chromatography, described by mean-field statistical thermodynamic theory, asserts that one principal driving force for solute retention is the creation of a solute-sized cavity in the stationary phase. Beyond a critical stationary phase bonding density, increased grafted chain density should
K B, Sentell, J G, Dorsey
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Retention properties of novel β-CD bonded stationary phases in reversed-phase HPLC mode

Talanta, 2009
With the given special structures, the CD bonded stationary phases are expected to have complementary retention properties with conventional C18 stationary phase, which will be helpful to enhance the polar selectivity in RP mode separation. In this work, two beta-cyclodextrin (beta-CD) bonded stationary phases for reversed-phase HPLC, including 1, 12 ...
Yanyan, Zhao   +7 more
openaire   +4 more sources

Fabrication and evaluation of tetraazahexaphenylmacrocycle-bonded stationary phase with multiple retention mechanisms

Journal of Chromatography A, 2021
A 34-membered tetraazahexaphenylmacrocycle (N4Ph6) with a rigid π-conjugated moiety was chemically bonded to silica gel with 3-chloropropyltrimethoxysilane as the coupling agent to prepare a novel SiO2@N4Ph6 stationary phase. Several common organic analytes, including alkylbenzenes, polycyclic aromatic hydrocarbons, anilines, phenols, phthalates, and ...
Junnan, Li   +6 more
openaire   +4 more sources

Retention of the stationary phase for high‐speed countercurrent chromatography

AIChE Journal, 2007
AbstractHigh‐speed countercurrent chromatography (HSCCC) is an emerging technique for preparative purification of a wide variety of solutes. Retention of the stationary phase is a crucial variable which is used for the derivation of the column efficiency, peak resolution, and solute retention.
He, Chao-Hong, Zhao, Chun-Xia
openaire   +4 more sources

A Survey of Polar Stationary Phases for Hydrophilic Interaction Chromatography and Recent Progress in Understanding Retention and Selectivity.

Biomedical chromotography, 2022
Various polar stationary phases have become available for hydrophilic interaction chromatography (HILIC) and help drive continuous applications in biomedical, environmental and pharmaceutical areas in the past decade.
Yong Guo
semanticscholar   +1 more source

Prospects of using hyperbranched stationary phase based on poly(styrene-divinylbenzene) in mixed-mode chromatography.

Journal of Chromatography A, 2021
Evaluation of the chromatographic properties of covalently bonded hyperbranched stationary phase based on poly(styrene-divinylbenzene) (PS-DVB) and containing zwitterionic fragments in the structure of functional layer was conducted in suppressed ion ...
A. Popov   +5 more
semanticscholar   +1 more source

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