Results 31 to 40 of about 2,833 (266)

How not to argue about immigration [PDF]

open access: yesFilozofija i Društvo, 2013
This paper describes and assesses the arguments offered both against closed borders and in favor of a more open borders approach to U.S. immigration reform as those arguments are set forth in R.
Corlett Angelo J., Unger Kimberly
doaj   +1 more source

Authoritarianism reconstituted: ‘hollow statism’ and the crackdown on Islamic movements in Sisi’s Egypt [PDF]

open access: yes, 2021
This dissertation analyses state-society relations in Egypt, focusing on Islamic movements and their social and religious service provision, as a lens to track changes in the form of authoritarianism deployed under the Sisi regime.
Russell, Neil
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Statism, Left or Right? A Critique of the Development Project of the Shah in Iran

open access: yesQuarterly Journal of Austrian Economics
In this article, we first provide a definition of the concept of statism and clarify its distinction from the idea of liberalism, which is based on respect for private property rights, in the way it confronts problems existing in societies. We then focus
Mehrpouya Ala
doaj   +1 more source

Luigi Sturzo sulla “Plain fascist economics” di Herbert Hoover [PDF]

open access: yesStoria e Politica
Sturzo during his exile in America intervened in the political debate dealing with various topics; diplomacy, society, problems of Catholics and also economic issues.
Vincenzo Pintaudi
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Society Despite the State

open access: yesACME, 2021
Geography as a discipline has its foundations in colonialist, imperialist, capitalist and nation-building endeavours. The state has been central to its institutionalisation and has shaped in many ways the epistemic frameworks that continue to dictate ...
Gerónimo Barrera, Anthony Ince
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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