Results 121 to 130 of about 803,751 (294)
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
An Extension of Wald's Theory of Statistical Decision Functions [PDF]
Lucien LeCam
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Geometrically synchronous watermarking algorithm based on the corner feature
Simple geometric attacks could destroy watermark or its position,causing the failure of most watermarking algorithm.A geometrically synchronous watermarking algorithm robust based on the corner feature was proposed.In this paper,the feature point was ...
LIU Quan1+5 more
doaj
On an Application of Kronecker Product of Matrices to Statistical Designs [PDF]
M. N. Vartak
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Statistical methods used in the measurement of radioactivity with some useful graphs and nomographs.
A.A. Jarrett
openalex +1 more source
On the Theory of Unbiased Tests of Simple Statistical Hypotheses Specifying the Values of Two or More Parameters [PDF]
Stanley L. Isaacson
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Statistical Treatment of Joints and Structural Analysis: No., 2., Cleavage Plane
Takao Yamaguchi
openalex +2 more sources