Statistical analysis of PML incidences of natalizumab-treated patients from 2009 to 2016: outcomes after introduction of the Stratify JCV® DxSelect™ antibody assay [PDF]
Denise I. Campagnolo +5 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Natriuretic peptides testing and survival prediction models for chronic heart failure: a systematic review of added prognostic value. [PDF]
Smith CA +8 more
europepmc +1 more source
Statistical model for collisions and recollisions of inertial particles in mixing flows [PDF]
K. Gustavsson, B. Mehlig
openalex +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Independent Increments and Group Sequential Tests. [PDF]
Tsiatis AA, Davidian M.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Incidence and Predictors of Symptom-Arrhythmia Association During Outpatient Holter Monitoring. [PDF]
Saraiya A +5 more
europepmc +1 more source
Statistical Characteristics of Gravity Waves With Near‐Inertial Frequencies in the Antarctic Troposphere and Lower Stratosphere Observed by the PANSY Radar [PDF]
Yuichi Minamihara +3 more
openalex +1 more source

