Results 81 to 90 of about 803,751 (294)

An overview: the impact of data mining applications on various sectors

open access: yesTehnički Glasnik, 2017
In recent years, it has become difficult to reach to the reliable information with increasing complicated, non-significant, unclear, large and raw data.
Mümine Kaya Keleş
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

An approximation theorem and generic convergence for equilibrium problems

open access: yesJournal of Inequalities and Applications, 2018
In this paper, we prove an approximation theorem for equilibrium problems and provide theoretical support for many algorithms. Simon’s bounded rationality is illustrated by an approximation theorem, that is, bounded rationality is approaching full ...
Xiaoling Qiu, Wensheng Jia, Dingtao Peng
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

STATISTICS.

open access: yesThe American Journal of the Medical Sciences
n ...
openaire   +2 more sources

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