Results 111 to 120 of about 11,222,791 (325)

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Forecasting the monthly retail sales of electricity based on the semi-functional linear model with autoregressive errors

AIMS Mathematics
In many statistical applications, data are collected sequentially over time and exhibit autocorrelation characteristics. Ignoring this autocorrelation may lead to a decrease in the model's prediction accuracy. To this end, assuming that the error process
Bin Yang, Min Chen, Jianjun Zhou
doaj   +1 more source

Sequential Analysis of Statistical Data [PDF]

, 1946
M. G. Kendall
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

How can we attract and keep young talents in the science sector? Work satisfaction and the inclination to change your workplace

Marketing of Scientific and Research Organizations, 2019
Gradually dropping number of working age people, dropping rate of unemployment and continuously growing number of job vacancies, which remain open for a longer time, lead to a situation in which more and more often in the context of Poland people say the
Feldy Marzena
doaj   +1 more source

An Application of Statistical Methods to Core Analysis Data of Dolomitic Limestone [PDF]

, 1946
A.C. Bulnes
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

A Multiple Regression Model Analysing Additional Sources of Dietary Fibre as a Factor Affecting the Development of the Gastrointestinal Tract in Broiler Chickens

Applied Sciences
The objective of this study was to compare the effects of applying a 50% wheat grain diet with those of a diet with 3% additional dietary fibre from various sources on the development of broiler chickens’ gastrointestinal tract and its related organs and
Tomasz Hikawczuk, Patrycja Wróblewska, Anna Szuba-Trznadel, Agnieszka Rusiecka, Andrii Zinchuk, Krystyna Laszki-Szcząchor   +5 more
doaj   +1 more source

Ethos of science and the approach to promotion in science

Marketing of Scientific and Research Organizations, 2018
The quality of research is the most important feature in the world of science. A researcher who achieves an excellence in science has a chance to win recognition and gain authority in her scientific field.
Feldy Marzena
doaj   +1 more source