Results 141 to 150 of about 11,222,791 (325)
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Improving Statistical MT through Morphological Analysis [PDF]
Goldwater, Sharon, McClosky, David
core +1 more source
Statistical Analysis Through Factors Path Method [PDF]
The present research reflects the importance in statistics of the „Factors Path Method” (FPM), which provides modern techniques for the reflection of the factorial influences over of the variation in time or space presented by the phenomenons from ...
Gabriela OPAIT
core
Statistical Analysis in Chemistry and the Chemical Industry C. A. Bennett and N. L. Franklin. New York, John Wiley and Sons, Inc., 1954, 724 pp. $8.00 [PDF]
openalex +3 more sources
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
A Microbiological Assay of Inositol: its Development and Statistical Analysis
B.E. Northam, F. W. Norris
openalex +1 more source