Results 251 to 260 of about 11,657,504 (319)

Leveraging word embeddings to enhance co-occurrence networks: A statistical analysis. [PDF]

PLoS One
Amancio DR, Machicao J, Quispe LVC.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Statistical Analysis and Reporting of Cardiac Output Method Comparison Studies (COMPARE) Statement. [PDF]

Anesthesiology
Saugel B, Hapfelmeier A, Flick M, Rinehart J, Thiele RH, Vistisen ST, Bartels K, Cannesson M, Cecconi M, Chew MS, De Backer D, Joosten A, Khanna AK, Levy JH, Meidert AS, Messina A, Monnet X, Myatra SN, Pinsky MR, Turan A, van der Horst ICC, Vincent JL, Kouz K.   +22 more
europepmc   +1 more source

Statistical analysis of links between blocks of variables

, 2019
Stéphanie Bougeard
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Assessment of the Risk of Venous Thromboembolism in Overcrowded Shelters: A Geospatial and Statistical Analysis of the 2024 Noto Peninsula Earthquake. [PDF]

Cureus
Nakai H, Horiike R, Itatani T, Tokuoka M, Maeda A, Iida H, Aoki Y, Toda D, Oe M.   +8 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Simultaneous effects of temperature, holding time and thickness on bending springback of DP1000 steel: experiments and statistical analysis. [PDF]

Sci Rep
Karalar M, Bayramoglu M.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source