Results 241 to 250 of about 199,661 (312)

Parallel algorithms for phylogenetic inference under a structured coalescent approximation. [PDF]

Proc Natl Acad Sci U S A
Shao Y, Suchard MA, Rambaut A, Ji X, Lemey P, Vasylyeva TI, Baele G.   +6 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Automated H-Scoring in Muscle-Invasive Bladder Cancer IHC: An Internal Validation Study. [PDF]

Diagnostics (Basel)
Yap M, Mihai IM, Alanazi MAA, Olteanu GE, Contreras-Sanz A, Black P, Wang G.   +6 more
europepmc   +1 more source

A blockchain-enabled framework for secure and efficient data transmission in underwater sensor networks using advanced cryptographic techniques. [PDF]

Sci Rep
Kumar KK, Pavani M, Chandra NS, Chitralingappa P, Kumar BH, Anushree G.   +5 more
europepmc   +1 more source

Privacy preserving digital platform for patient reported outcomes in inflammatory bowel disease. [PDF]

NPJ Digit Med
Ohta Y, Taida T, Ogasawara S, Aizu T, Konagaya T, Ota M, Koborita R, Suzuka R, Ito T, Ozeki Y, Furuya M, Shu N, Horio R, Nagashima A, Shiratori W, Yokoyama Y, Nakamura M, Okimoto K, Saito K, Matsumura T, Nakagawa T, Shimazu M, Sakurai Y, Yoshimura K, Kato J.   +24 more
europepmc   +1 more source

Quantifying energy and accuracy trade-offs of federated learning on wearable health devices. [PDF]

Front Big Data
S R, Khekare G, Kumar Y, Soni G.
europepmc   +1 more source

Theory of temporal pattern learning in echo state networks. [PDF]

PNAS Nexus
Hakim V, Karma A.
europepmc   +1 more source