Results 251 to 260 of about 6,153,719 (345)

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

open access: yesAdvanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park   +4 more
wiley   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

open access: yesAdvanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar   +9 more
wiley   +1 more source

Engineering Volumetric Tissue Analogs via Assembly of Endothelial Cell‐Covered Spheroidal Microtissues

open access: yesAdvanced Healthcare Materials, EarlyView.
An engineering strategy to fabricate highly vascularized volumetric tissues with capillary networks is developed. Endothelial cell‐covered spheroidal microtissues with high structural integrity are efficiently produced using bioprinting technology. These spheroidal microtissues are then assembled and cultured under perfusion conditions, resulting in ...
Hyeongkwon Oh   +5 more
wiley   +1 more source

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