Results 61 to 70 of about 976,015 (308)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Statistical and Ideal Convergences in Topology

open access: yesMathematics, 2023
The notion of convergence wins its own important part in the branch of Topology. Convergences in metric spaces, topological spaces, fuzzy topological spaces, fuzzy metric spaces, partially ordered sets (in short, posets), and fuzzy ordered sets (in short,
D. Georgiou, G. Prinos, F. Sereti
doaj   +1 more source

Poisson Convergence for Dissociated Statistics

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1984
SUMMARY A Poisson limit theorem is derived for the number of “large” values observed among comparisons of independent, but not necessarily identically distributed random variables. The comparisons made need not be the same and may depend on the two variables being compared. An application to the assessment of large numbers of correlation
Barbour, A D, Eagleson, G K
openaire   +3 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

A Bit of Information Theory, and the Data Augmentation Algorithm Converges

open access: yes, 2008
The data augmentation (DA) algorithm is a simple and powerful tool in statistical computing.
Yu, Yaming
core   +2 more sources

Fundamental properties of statistical convergence and lacunary statistical convergence on time scales [PDF]

open access: yesFilomat, 2017
In this paper, we first obtain a Tauberian condition for statistical convergence on time scales. We also find necessary and sufficient conditions for the equivalence of statistical convergence and lacunary statistical convergence on time scales. Some significant applications are also presented.
Turan, Ceylan, Duman, Oktay
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

On I-statistically rough convergence

open access: yesPublications de l'Institut Mathematique, 2019
We introduce rough I-statistical convergence as an extension of rough convergence. We define the set of rough I-statistical limit points of a sequence and analyze the results with proofs.
Savaş, Ekrem   +2 more
openaire   +2 more sources

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