Results 61 to 70 of about 6,153,719 (345)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Some properties of $I_3$-λ-statistical cluster points

Dera Natung Government College Research Journal, 2022
In this note, we investigate some problems concerning the set of λ-statistical cluster points of triple sequences via ideals in finite dimensional spaces, and some of its properties in finite dimensional Banach spaces are proved.
Verda Gürdal, Ömer Kişi
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

On the convergence to statistical equilibrium for harmonic crystals

, 2002
We consider the dynamics of a harmonic crystal in $d$ dimensions with $n$ components, $d,n$ arbitrary, $d,n\ge 1$, and study the distribution $\mu_t$ of the solution at time $t\in\R$.
A. I. Komech, Boldrighini, Dudnikova, Dudnikova, Dudnikova, Dudnikova, Dudnikova, Fedoryuk, H. Spohn, Rosenblatt, Shuhov, Spohn, T. V. Dudnikova   +12 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Iterative Determination of Distributions by the Monte Carlo Method in Problems with an External Source

, 2013
In the Monte Carlo (MC) method statistical noise is usually present. Statistical noise may become dominant in the calculation of a distribution, usually by iteration, but is less Important in calculating integrals.
Makai, Mihály, Szatmáry, Zoltán
core   +1 more source

Spaces of neutrosophic λ -statistical convergence sequences and their properties

, 2020
In this paper, we use the notion of λ-statistical convergence in order to generalize these concepts. We establish some inclusion relations between them. We define the statistical convergence and λ-statistical convergence in neutrosophic normed space.
V. Khan, Hira Fatima, M. Khan, Ayaz Ahamd   +3 more
semanticscholar   +1 more source

Statistical convergence of the EM algorithm on Gaussian mixture models [PDF]

Electronic Journal of Statistics, 2018
We study the convergence behavior of the Expectation Maximization (EM) algorithm on Gaussian mixture models with an arbitrary number of mixture components and mixing weights. We show that as long as the means of the components are separated by at least $\
Ruofei Zhao, Yuanzhi Li, Yuekai Sun
semanticscholar   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Poisson Convergence for Dissociated Statistics

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1984
SUMMARY A Poisson limit theorem is derived for the number of “large” values observed among comparisons of independent, but not necessarily identically distributed random variables. The comparisons made need not be the same and may depend on the two variables being compared. An application to the assessment of large numbers of correlation
Barbour, A D, Eagleson, G K
openaire   +3 more sources