Results 221 to 230 of about 46,356,444 (275)

Effects of a maternal ketogenic diet on maternal and offspring metabolic health in mice. [PDF]

PLoS One
Ruano AH, Kracaw RA, Cervantes IA, Ruano SH, Tacam MJ, Pennington KA.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Statistical Characterization of Received Signal Power for Spectrum-Based GNSS Interference Detection. [PDF]

Sensors (Basel)
Bronk K, Koncicki P, Lipka A, Niski R, Stroynowski W, Wereszko B.   +5 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

A joint mixture Tobit method with latent microbial abundance improves detection of microbiome-disease associations in zero-inflated data. [PDF]

PLoS Comput Biol
Deng J, Chen D, Shen S, Zhou Y, Cui H, Qiu Y, Li Q, Hu YQ.   +7 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

EPA and DHA engage NRF2 to orchestrate a β-cell resilience circuit suppressing senescence remodeling and sustaining molecular fitness during glucolipotoxic stress. [PDF]

Front Physiol
Xing C, Li F, Zou Y, Song C, Luo D, Ruan J, Tang M, Xu Q, Mu Y, Shen J, Zhao AZ.   +10 more
europepmc   +1 more source

A self-supervised reconstruction framework for segment-level detection of task-induced deviations in multi-channel EEG. [PDF]

PLoS One
Saavedra LA, Quintero-Rincón A, Batatia H.   +2 more
europepmc   +1 more source

Haemodynamic and Respiratory Effects of Dexmedetomidine as an Adjuvant to Oxycodone Patient-Controlled Analgesia After Lumbar Spinal Fusion: A Post Hoc Analysis of the DoseRespDex Randomised Controlled Trial. [PDF]

Acta Anaesthesiol Scand
Mäkelä S, Saari TI, Löyttyniemi E, Aantaa R, Liukas A, Uusalo P.   +5 more
europepmc   +1 more source

Perceived gym service quality, leisure boredom, and loneliness among leisure sport participants: a cross-sectional study. [PDF]

Front Psychol
Tapşın FO, Çakmak G, Tapşın FO.
europepmc   +1 more source