Results 111 to 120 of about 11,717,635 (369)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
A statistical model for estimating mean maximum urban heat island [PDF]
, 2003 Investigations concentrated on the urban heat island (UHI) in its strongest development during the diurnal cycle. Task includes development of statistical models in the heating and non-heating seasons using urban surface parameters (built-up and water ...
Balázs, Bernadett +4 more
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Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Association between dietary patterns and depressive symptoms in adult women living in Tehran (2013)
The Journal of Qazvin University of Medical Sciences, 2015 Background: Depression is one of the most common mental illnesses. Few studies have investigated the association between dietary patterns and depression in developing countries.
M. Lahouti +4 more
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The Warsaw – Lodz Duopolis in the light of the changes in the urban population density [PDF]
, 2013 The article presents the changes in the urban population density in the 20th c., in central Poland, in an area where the two largest Polish cities – Warsaw and Lodz are situated, within a distance of 120 km from each other.
Jażdżewska, Iwona
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Transforming a Patient Registry Into a Customized Data Set for the Advanced Statistical Analysis of Health Risk Factors and for Medication-Related Hospitalization Research: Retrospective Hospital Patient Registry Study [PDF]
, 2021 Zhivko Taushanov +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
STATISTICAL FACTOR ANALYSIS OF THE SLAGS CHARACTERISTICS OF STEEL-MAKING
Литьë и металлургия, 2005 The regression equations, reflecting interaction of the slag characteristics and its chemical composition, are received on the basis of multivariate regressive analysis using empirical evidence.
V. F. Sobolev +2 more
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