Results 121 to 130 of about 11,717,635 (369)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Statistical Analysis of Details and Factors of 1920s Famine in the Tatar Republic

open access: diamond, 2020
Milyausha A. Akhmetova   +1 more
openalex   +1 more source

Space station software reliability analysis based on failures observed during testing at the multisystem integration facility [PDF]

open access: yes
Quality of software not only is vital to the successful operation of the space station, it is also an important factor in establishing testing requirements, time needed for software verification and integration as well as launching schedules for the ...
Tamayo, Tak Chai
core   +1 more source

The effect of round-off error on long memory processes

open access: yes, 2013
We study how the round-off (or discretization) error changes the statistical properties of a Gaussian long memory process. We show that the autocovariance and the spectral density of the discretized process are asymptotically rescaled by a factor smaller
La Spada, Gabriele, Lillo, Fabrizio
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Structural equation modeling in epidemiology

open access: yesCadernos de Saúde Pública
Structural equation modeling (SEM) is an important statistical tool for evaluating complex relations in several research areas. In epidemiology, the use and discussion of SEM have been limited thus far. This article presents basic principles and concepts
Leila Denise Alves Ferreira Amorim   +10 more
doaj  

Commodity prices, commodity currencies, and global economic developments [PDF]

open access: yes
In this paper we seek to produce forecasts of commodity price movements that can systematically improve on naive statistical benchmarks, and revisit the forecasting performance of changes in commodity currencies as efficient predictors of commodity ...
Jan J.J. Groen, Paolo A. Pesenti
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Reliability and validity of the Italian version of the 14-item Resilience Scale

open access: yesPsychology Research and Behavior Management, 2016
Camilla Callegari,1 Lorenza Bertù,2 Melissa Lucano,1 Marta Ielmini,1 Elena Braggio,1 Simone Vender1 1Department of Clinical and Experimental Medicine – Psychiatric Division, 2Department of Clinical and Experimental Medicine, Centre for ...
Callegari C   +5 more
doaj  

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