Results 171 to 180 of about 6,703,122 (335)

The Quality of Education at a Key Factor of the Population’s Living Standards (Exemplified by the Statistical Analysis of the Canadian Education System)

, 2019
Oleg A. Radchenko
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Ying Zhou and Xinyi Zhang's contribution to the Discussion of ‘Vintage Factor Analysis with Varimax Performs Statistical Inference’ by Rohe & Zeng [PDF]

, 2023
Ying Zhou, Xinyi Zhang
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The Application of Statistical Package for the Social Sciences into Data Analysis to Identify and Evaluate the Risk Factors Influencing to the Implementation of the Renovation and Improvement National Highway 53, Tra Vinh - Long Toan Section, Tra Vinh Province, Vietnam

, 2021
Anh Tuan Nguyen, Truong Vu Pham
openalex   +1 more source

Risk factors for persistent fatal opioid-involved overdose hotspots in Massachusetts 2011- 2021: A spatial statistical analysis with socio-economic, access and prescription factors [PDF]

, 2023
Sumeeta Sriniva, Jennifer Pustz, Elizabeth Marsh, Leonard D. Young, Thomas J. Stopka   +4 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Construct validation of students’ anxiety and attitudes towards statistical concepts questionnaire: An exploratory factor analysis procedure [PDF]

Fadila Amira Razali, Sharifah Norhuda Syed Wahid, Noor Izyan Mohamad Adnan, Nik Muhammad Farhan Hakim Nik Badrul Alam, Zulkifli Ab Ghani Hilmi   +4 more
openalex   +1 more source

An Inferential Statistical Analysis of the Key Factors Influencing the Adoption of New Technology by MEEC (MICE) Organizers in Thailand

, 2023
Vithaya Sintharapantorn, Jeffrey Alan Simcox   +1 more
openalex   +2 more sources