Results 201 to 210 of about 6,703,122 (335)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dose-Response Efficacy and Safety of Factor XI/XIa Inhibitors in Atrial Fibrillation; a Systematic Review and Meta-Analysis With Subgroup Exploration and Trial Sequential Validation. [PDF]

Clin Cardiol
Faizan MA, Rehman T, Dandamudi M, Menon JA, Ferrara VZ, Kholeif Z, Tanvir A, Saeed F, Ikram J, Chaudhri M, Espiche C, Aslam MMS, Humayun Z, Khalid AM, Waqas SA, Ahmad R, Cerna L.   +16 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Development of the Japanese Version of the Brief Dimensional Apathy Scale (b-J-DAS): Multidimensional Apathy in Dementia. [PDF]

Psychogeriatrics
Hirayama Y, Takebayashi M, Fukuhara R, Kawagoe T.   +3 more
europepmc   +1 more source

Research on the influence factors of real driving cycle with statistical analysis and dynamic time warping [PDF]

, 2018
Shu Yu, Lin Lü
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Theoretical Discussion of Applicability and a Practical Example of Using Statistical Second-Generation Techniques to Analyze Causal Relationships in Animal Experiments. [PDF]

Animals (Basel)
Katrin B.
europepmc   +1 more source

A study on the problems of caries prevalence in permanent teeth of school children during compulsory education. The statistic decomposition of factors in the cumulative analysis of variance of multiple-way layout.

, 1986
T Morita
openalex   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Factors predicting adverse perinatal outcomes in women presenting with decreased fetal movements. [PDF]

Cochrane Database Syst Rev
Haakons KL, Low-Choy S, Bradford B, Heazell A, Gordon A, Andrews C, Flenady V.   +6 more
europepmc   +1 more source