Results 251 to 260 of about 8,264,393 (332)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Methods for Analytical Validation of Novel Digital Clinical Measures: Implementation Feasibility Evaluation Using Real-World Datasets.

J Med Internet Res
Turner S, Floden L, Simmatis L, Fromy P, Langford J, Daza EJ, Potter A, Troeger K, STAGES cohort investigator group.   +8 more
europepmc   +1 more source

METTL3 inhibition alleviates neuroinflammation and apoptosis by reducing ETV4 m6A modification. [PDF]

Front Immunol
He D, Jiang X, Guo G, Ma J, Chen J, Zhang Y, Zhuang J, Xie P, Zhang Z.   +8 more
europepmc   +1 more source

A Tutorial on Evaluating Confirmatory Factor Analysis with lavaan and dynamic: Integrating Statistical and Conceptual Approaches

Thomas Boivin, Charles Veilleux, Maya Egerton-Graham, Pier-Olivier Caron, Patrick Gaudreau   +4 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Adaptation and psychometric validation of the Turkish version of the motivation for healing scale in patients with cancer. [PDF]

Asia Pac J Oncol Nurs
Uğuz Ö, Keskin G.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

NRF1 is upregulated by docosahexaenoic acid to ameliorate MASH through the inhibition of ER stress. [PDF]

Cell Death Dis
Lin M, Zhang H, Chen S, Zhang J, Tang C, Song X, Zhou J, Xu Z, Mu Y, Zeng H, Yang C, Yu C, Xu C.   +12 more
europepmc   +1 more source

A multivariate statistical study with a factor analysis of recent planktonic foraminiferal distribution in the Coromandel Coast of India

, 1991
K.V. Jayalakshmy, K. Kameswara Rao
openalex   +1 more source

Factors Influencing Apartment Rental Prices in Kuala Lumpur: A Statistical Analysis

Nur Shamilah Shah Kirit, Nurin Nazirah Tarmizi, Nurul Ain Athirah Mohd Saamah, Siti Norfazlina Yusoff, Noraini Ahmad   +4 more
openalex   +1 more source