Results 281 to 290 of about 6,703,122 (335)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Reply to correspondence on "The importance of data transformation in correlation analysis of FVIII and inhibitor titers in acquired hemophilia". [PDF]

Res Pract Thromb Haemost
Yu D, Liu W, Zhang L.
europepmc   +1 more source

Multivariate Statistical Analysis for Exploring Road Crash Related Factors in the Franche-Comté region of France

, 2020
Cécile Spychala, Joël Armand, Clément Dombry, Camélia Goga   +3 more
openalex   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

SENP3 drives colorectal cancer progression by enhancing GDF15 expression. [PDF]

Int J Colorectal Dis
Yu Y, Bao W, Chen J, Li Y, Gao Y.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Age-Stratified Effects of Diabetes Mellitus on Central Nervous System Tuberculosis Risk and Combined Effects with Neutrophil-to-Lymphocyte Ratio. [PDF]

Infect Drug Resist
Chen M, Fan X, Chen Y, Zhang F, Yao Z, Lin Y, Chen X, Wu D.   +7 more
europepmc   +1 more source

Statistical Analysis of the Role of Socio-Demographic and Health Factors in Shared Mobility Related Behaviors and Usage Likelihoods

, 2019
Natalia Barbour
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

L-kynurenine reshapes immune microenvironment to alleviate methamphetamine-induced chronic lung injury through gut-lung axis. [PDF]

Microbiome
Ma PJ, Li M, Hu WT, Yang D, Liang YK, Chen L, Wang X, Pan Y, Wang Y.   +8 more
europepmc   +1 more source