Results 301 to 310 of about 11,717,635 (369)

Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank, Benjamin M. Jacobs, Jonathan Bestwick, Ruth Dobson   +3 more
wiley   +1 more source

METTL3-mediated m6A modification of LINC00857 enhances stemness and metastasis of ovarian cancer cells by activating the YAP-TEAD pathway. [PDF]

Sci Rep
Lin X, Hong Y, You S, Li P, Lv Y, Zheng J, Sun P.   +6 more
europepmc   +1 more source

Longitudinal Study of Salivary Biomarkers in the Definition of Clinico‐Molecular Progression of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
Longitudinal changes in salivary biomarkers in Parkinson’s disease (PD) from early (T0) to 4‐year follow‐up (T1), quantified by ELISA: oligomeric and total α‐synuclein, total and phosphorylated tau, MAP1LC3B (autophagy), and TNFa (inflammation). Blue arrows indicate direction of change at T1 vs T0 (up = increase; down = decrease).
Maria Ilenia De Bartolo, Daniele Belvisi, Matteo Costanzo, Claudia Caturano, Francesco Emanuele Bellomi, Carolina Cutrona, Flavia Aiello, Giorgio Leodori, Massimo Marano, Romina Mancinelli, Antonella Conte, Giovanni Fabbrini, Alfredo Berardelli, Giorgio Vivacqua   +13 more
wiley   +1 more source

Revealing gait as a murine biomarker of injury, disease, and age with multivariate statistics and machine learning. [PDF]

Sci Rep
Naved BA, Han S, Koss KM, Kando MJ, Wang JJ, Chang J, Weiss C, Passman MG, Wertheim JA, Luo Y, Zhang ZJ.   +10 more
europepmc   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway. [PDF]

Int J Mol Med
Xiao L, Qu M, Chen L, Xiang M, Long Q, Liu J, Guan X, Liao C.   +7 more
europepmc   +1 more source

Designing a management model for outsourcing non-clinical services in public hospitals in Iran. [PDF]

BMC Health Serv Res
Merati S, Nasiripour AA, Riahi L, Hajinabi K.   +3 more
europepmc   +1 more source

Neuroprotection of IGF-1 in neonatal hypoxic-ischemic brain injury through downregulation of FoXO3a-PUMA pathway. [PDF]

Front Cell Neurosci
Tang Y, Zhong R, Liang J, Liu S, Liu W, Liu T, Yuan B, Jiao M, Yin H.   +8 more
europepmc   +1 more source

Bayesian analyses for research on Alzheimer's disease and related disorders-updating one's knowledge. [PDF]

Alzheimers Dement (Amst)
Teipel S, Lutz M.
europepmc   +1 more source

Adolescents' attitudes towards healthy eating: A scale development study. [PDF]

PLoS One
Eşkil R, Eşkil KG, Yarım İ.
europepmc   +1 more source