Results 61 to 70 of about 6,703,122 (335)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Dietary patterns and associated factors among the elderly

Revista Brasileira de Geriatria e Gerontologia, 2017
The aim of the present study was to identify dietary patterns among the elderly, and associate the same with sociodemographic characteristics, health and lifestyle.
Marcela Previato do Nascimento Ferreira, Ágatha Nogueira Previdelli, Tatiana Império de Freitas, Karina Maffei Marques, Rita Maria Monteiro Goulart, Rita de Cássia de Aquino   +5 more
doaj   +2 more sources

Effective factors in dealing with industrial crises caused by widespread virus outbreaks

Social Determinants of Health, 2023
Background: The global spread of the COVID-19 virus has not only posed a severe threat to public health but has also triggered a profound economic crisis affecting numerous industries. Addressing and mitigating the economic repercussions of the pandemic
MahdiReza Adamian, Abbas Toloie Eshlaghy, Reza Radfar, Alireza Pour Ebrahimi   +3 more
doaj   +1 more source

Statistical Analysis of Factors Influencing the Per Capita Disposable Income of Urban Residents in Anhui Province [PDF]

, 2023
Jiangshuang Huang
openalex   +1 more source

Statistical Analysis of Nonlinear Processes Based on Penalty Factor [PDF]

Mathematical Problems in Engineering, 2014
A new process monitoring approach is proposed for handling the nonlinear monitoring problem in the electrofused magnesia furnace (EFMF). Compared to conventional method, the contributions are as follows: (1) a new kernel principal component analysis is proposed based on loss function in the feature space; (2) the model of kernel principal component ...
Zhang, Yingwei, Zhang, Chuanfang, Zhang, Wei   +2 more
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Factor structure, internal consistency and reliability of the Posttraumatic Stress Disorder Checklist (PCL): an exploratory study Estrutura fatorial, consistência interna e confiabilidade do Posttraumatic Stress Disorder Checklist (PCL): um estudo exploratório

Trends in Psychiatry and Psychotherapy, 2012
INTRODUCTION: Posttraumatic stress disorder (PTSD) is an anxiety disorder resulting from exposure to traumatic events. The Posttraumatic Stress Disorder Checklist (PCL) is a self-report measure largely used to evaluate the presence of PTSD. OBJECTIVE: To
Eduardo de Paula Lima, Sandhi Maria Barreto, Ada Ávila Assunção   +2 more
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Digital morphometry of cytologic aspirate endometrial samples [Digitalna morfometrijska analiza citoloških uzoraka aspirata endometrija] [PDF]

, 2010
Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for.
Babić, Damir, Barišić, Ana, Božikov, Jadranka, Ilić-Forko, Jadranka, Jurič, Danijela, Mahovlić, Vesna, Ovanin-Rakić, Ana, Rajhvajn, Sanda, Šamija Projić, Ivana, Škopljanac-Mačina, Lada, Škrablin-Kučić, Snježana   +10 more
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