Results 81 to 90 of about 6,703,122 (335)
Confirmatory Factor Analysis of the Structure of Statistics Anxiety Measure: An Examination of Four Alternative Models [PDF]
Iranian Journal of Psychiatry, 2011 Objective: The aim of this study is to explore the confirmatory factor analysis results of the Persian adaptation of Statistics Anxiety Measure (SAM), proposed by Earp.Method: The validity and reliability assessments of the scale were performed on 298 ...
Hossein Bevrani, PhD +2 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
The application of multivariate statistical methods for understanding food consumer behaviour [PDF]
Understanding consumer behaviour is a necessary precondition for a targeted communication strategy. The behaviour is a complex phenomenon and research needs to undertake a rigorously apply sophisticated methods.
Banati, Diana +4 more
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Test of Convergence in Agricultural Factor Productivity: A Semiparametric Approach [PDF]
We tested for club convergence in U.S. agricultural total factory productivity using a sigma convergence test. We used the same club of states as used by McCunn and Huffman as well as different states within 10 clubs identified by the cluster analysis ...
Pandit, Mahesh +2 more
core +1 more source
The influence of random element displacement on DOA estimates obtained with (Khatri-Rao-)root-MUSIC [PDF]
, 2014 Although a wide range of direction of arrival (DOA) estimation algorithms has been described for a diverse range of array configurations, no specific stochastic analysis framework has been established to assess the probability density function of the ...
Inghelbrecht, Veronique +3 more
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
A statistical model for estimating mean maximum urban heat island [PDF]
, 2003 Investigations concentrated on the urban heat island (UHI) in its strongest development during the diurnal cycle. Task includes development of statistical models in the heating and non-heating seasons using urban surface parameters (built-up and water ...
Balázs, Bernadett +4 more
core