Results 71 to 80 of about 2,108,189 (231)

Statistical inference for Hicks–Moorsteen productivity indices

open access: yesAnnals of Operations Research
Abstract The statistical framework for the Malmquist productivity index (MPI) is now well-developed and emphasizes the importance of developing such a framework for its alternatives. In this paper, we try to fill this gap in the literature for another popular measure, known as the Hicks–Moorsteen productivity index (HMPI).
Léopold Simar   +2 more
openaire   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Reliability and Its Quantitative Measures [PDF]

open access: yes
In this article is made an opening for the software reliability issues, through wide-ranging statistical indicators, which are designed based on information collected from operating or testing (samples).
Alexandru ISAIC-MANIU
core  

Philadelphia: The State of the City -- A 2010 Update [PDF]

open access: yes, 2010
Provides an updated statistical portrait of the city, based on indicators for jobs and the economy, crime rates, enrollment in public and charter schools, population growth, home prices, size of city government, and residents' top ...

core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Indicators to Measure Violence Against Women [PDF]

open access: yes, 2007
1. This paper is prepared for the UN Expert Group Meeting on indicators to measure violence against women. The Expert Group Meeting is intended to support the work of the Statistical Commission and the Commission on the Status of Women in developing ‘a ...
Walby, S.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Analytic Amplitude Models for Forward Scattering [PDF]

open access: yes, 2000
We report on fits of a large class of analytic amplitude models for forward scattering against the comprehensive data for all available reactions. To differentiate the goodness of the fits of many possible parametrizations to a large sample of data, we ...
Cudell, J. R.   +7 more
core   +2 more sources

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