Results 81 to 90 of about 2,108,189 (231)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Analysis of Economic Indicators Using Statistical Methods [PDF]

, 2012
Předmětem této bakalářské práce je analýza vybraných makroekonomických ukazatelů 4 členských států Evropské Unie pomocí statistických metod. Pomocí těchto metod jsou analyzovány dosavadní výsledky ukazatelů a následně odhadnuty prognózy pro další vývoj ...
Ševčík, Jakub
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Altered Cardiac Autonomic Regulation in Overweight and Obese Subjects: The Role of Age-and-Gender-Adjusted Statistical Indicators of Heart Rate Variability and Cardiac Baroreflex. [PDF]

Front Physiol, 2020
Solaro N, Pagani M, Lucini D.
europepmc   +1 more source

Information-Geometric Indicators of Chaos in Gaussian Models on Statistical Manifolds of Negative Ricci Curvature

, 2007
A new information-geometric approach to chaotic dynamics on curved statistical manifolds based on Entropic Dynamics (ED) is proposed. It is shown that the hyperbolicity of a non-maximally symmetric 6N-dimensional statistical manifold M_{s} underlying an ...
A. Caticha, A. Caticha, A. Caticha, A. Manning, A.J. Scott, C. Cafaro, C. Chicone, C.M. Caves, C.R. Rao, C.W. Misner, Carlo Cafaro, D.P. Feldman, E.T. Jaynes, E.T. Jaynes, E.T. Jaynes, F. Benatti, F. Felice De, H.C. Ohanian, J.M. Lee, J.P. Eckmann, L. Casetti, M. Di Bari, M.P. do Carmo, R.A. Fisher, S. Amari, T. Kawabe, V.I. Arnold, W.H. Zurek, W.H. Zurek, W.H. Zurek   +29 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Aerospace Competitiveness: UK, US and Europe [PDF]

This paper assesses the UK aerospace industry’s competitiveness. Various statistical indicators are used to measure competitiveness, based on published data at the industry and firm level.
Derek Braddon, Keith Hartley
core  

The Effects of Information And Communication Technology In Hungarian Economic Sectors [PDF]

, 2011
As the author could not find a reassuring mathematical and statistical method in the literature for studying the effect of information communication technology on enterprises, the author suggested a new research and analysis method that he also used to ...
Sasvári, Péter László
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Investigating inter-turn fault in transformer using TTR and FRA [PDF]

, 2019
Transformers are one of the significant elements in the power system network. The Transformer function is to step up and down the voltages. When the transformer operating in high load, it exposes to failures.
Abdulrazzaq Al-Iedani, Ali Salman
core