Results 251 to 260 of about 15,642,380 (303)

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Enhancing validation of case-control omics signatures through "minimalist" single-subject analysis (N-of-1 trials): proof of concept in sepsis. [PDF]

J Am Med Inform Assoc
Wilson LS, Pouladi N, Nelson RF, Middleton EA, Tolley ND, Shabanian M, Kenost C, Campbell RA, Rondina MT, Lussier YA.   +9 more
europepmc   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Safety-Oriented Evaluation of Large Language Models in Health Care: Guideline-Informed Systematic Review. [PDF]

Online J Public Health Inform
Matsuoka H, Takahashi T, Semitsu T, Matsuoka K, Hayashi R.   +4 more
europepmc   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

From data collection to action: environmental health information management practices in eleven municipalities in the east coast of South Africa. [PDF]

Front Health Serv
Masimula SS, Flory Senekane M, Naicker N.   +2 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Machine Learning-Based Detection of Prophylactic Indication Mentions for Stress-Related Mucosal Disease in Chinese Clinical Progress Notes: Text Classification Study. [PDF]

JMIR Med Inform
Jiang W, Wang S, Liang H, Xu L, Hu J.
europepmc   +1 more source

REWARD-an open-source framework for identifying the unknown benefits of existing medications to inform drug discovery, development, and repurposing. [PDF]

J Am Med Inform Assoc
Kern DM, Bohn J, Gilbert JP, Knoll C, Ryan PB.   +4 more
europepmc   +1 more source

Effective approaches towards teaching human anatomy among MBBS students in India. [PDF]

Bioinformation
Krishna Kishore G, Periyasamy V, Deepa KS, Caroline Sangeetha J, Mohamed Ismail B, Ninganagouda P, Shivaleela C.   +6 more
europepmc   +1 more source